GTF2H1 and anemia (phenotype): rs4150558 (χ2 test P = 1.61 × 10−6; OR = 23.45, 95%CI:2.64–208.13, P = 0.005) in GTF2H1, rs2290280 (χ2 test P = 2.86 × 10−6; OR = 28.53, 95%CI:1.69–481.13, P = 0.020) in CCNH, rs8067195 (χ2 test P = 1.01 × 10−5; OR = 6.93, 95%CI:1.44–33.49, P = 0.016) and rs6416887 (χ2 test P = 3.07 × 10−5; OR = 6.55, 95%CI:1.32–32.44, P = 0.021) in RPA1 were significantly related to anemia in SCC (Fig. 1C) (Table 2).