CHST9 and metastatic malignant neoplasm in the lymph nodes: HRs, calculated from the multivariate Cox proportional hazards model, demonstrated that patients without lymph-node metastasis harboring CHST9 rs1436904 GG or GT/GG genotype showed 2.27-fold or 2.01-fold increased risk for disease progression (P = 0.033 or 0.017, respectively) compared to the TT genotype patients (Table 2).