In all, to the best of our knowledge, our study for the first time identified an inherited variation in CHST9 which was significantly associated with DFS of TNBC patients, especially in TNBC patients harboring big tumors, without lymph-node metastasis, being premenopausal at diagnosis or with vascular invasion. The gene discussed is CHST9; the disease is metastatic malignant neoplasm in the lymph nodes.