HMGA1 and breast carcinoma: In order to verify whether these properties are at least in part regulated by HMGA1-dependent SPs, we evaluated the effect of affinity purified GPs obtained from shA1_3 I and NI cells on the proliferation and migratory properties of the MDA-MB-468 breast cancer cell line, a TNBC cell line that can be used as suitable model for both EMT and MET12,13.