While the presence of other CD11b+ myeloid populations (CD11b+ CD11c− Gr-1−) remained constant (Fig. 1c and Supplementary Fig. 1d), DCs (CD11c+ MHC-II+) accumulated at significantly lower numbers in tumours of MK2ΔCD11c mice (Fig. 1c and Supplementary Fig. 1d). This evidence concerns the gene ITGAM and neoplasm.