Bridging integrator 2 (BIN2), Thromboxane A synthase 1(TBXAS1), and Transmembrane protein 119 (TMEM119) were the most significantly upregulated genes, and elongator acetyltransferase complex subunit 3 (ELP3), and Heat shock protein family A (Hsp70) member 9 (HSPA9), and Huntingtin interacting protein 1 related (HIP1R) were the most significantly downregulated genes between the A and OD samples. The gene discussed is HIP1R; the disease is osteochondritis dissecans.