Interestingly, one of these regions, 8q24.3 contains: the c-Myc gene; GSDMD, encoding inflammasome substrate gasdermin D (Liang and Liu, 2016); and a novel, uncharacterised locus of resistance to severe malaria (Malaria Genomic Epidemiology Network et al., 2015). The gene discussed is GSDMD; the disease is malaria.