Furthermore, conditioned medium from the RCC cell lines ACHN, 786-O and MAR that secrete high levels of CXCR2 ligands enhanced the migration of CXCR2-transduced NK cells 2- to 2.5-fold compared with NGFR-transduced NK cells (Fig. 5f). The gene discussed is CXCR2; the disease is renal cell carcinoma.