While the underlying cause of the cytokine dysregulation we have found here is not known, decreased IL-2 [45], increased IL-6 [46], IL-8 and TNFα [47] have all been associated with Toxoplasma gondii infections, of which the seroprevelance is increased in schizophrenia [48]. The gene discussed is CXCL8; the disease is schizophrenia.