CFTR and cystic fibrosis: Genetic defects in CFTR are well known for their causative role in cystic fibrosis (CF), and are linked to the pathogenesis of an array of other disorders including idiopathic bronchiectasis [2, 3], chronic sinusitis [4], allergic bronchopulmonary aspergillosis [5], congenital bilateral absence of the vas deferens [6], and recurrent idiopathic pancreatitis [7, 8].