EGFR and neoplasm: Many genes in these chromosome lesions, such as EGFR (amp 7p11.2) (Eichler et al., 2010), MET (amp 7q31.2) (Breindel et al., 2013; Lutterbach et al., 2007), KRAS (amp 12p12.1) (Schmid et al., 2009), and CACNA2D2 (del 3p21.31) (Warnier et al., 2015), are known to be related to tumor invasion and metastasis.