ERBB2 and cancer: Only 23.8% of patients with luminal A tumors (32 of 134) experienced distant cancer recurrence, a rate that differed significantly from the total recurrence rates of patients with HER2-positive luminal B (42.5%, 17 of 40) and non-luminal HER2-positive tumors (52.3%, 11 of 21) (Table 9).