In the absence of TLR stimulation, CD203c expression levels in healthy subjects (265.897 ± 34.449), patients with type 1 AIP (238.364 ± 17.130), ACP (235.84 ± 44.43), bronchial asthma (251.546 ± 50.610), and atopic dermatitis (194.674 ± 49.491) in mean fluorescence intensity (MFI) were not significantly different, and the ratio of activated basophils in healthy subjects (2.758 ± 0.144%), patients with type 1 AIP (3.167 ± 0.156%), patients with ACP (2.256 ± 0.133%), bronchial asthma (3.489 ± 0.282%), and atopic dermatitis (2.946 ± 0.118%) were also not significantly different (data not shown). Here, ENPP3 is linked to atopic eczema.