However, the ratios of basophils activated by TLR4 stimulation in the blood of patients with type 1 AIP (9.875 ± 1.148%) and atopic dermatitis (11.768 ± 1.899%) were significantly higher than that in healthy subjects (5.051 ± 0.730%; P < 0.05). This evidence concerns the gene TLR4 and atopic eczema.