TMIGD2 and colorectal carcinoma: Analysis of phosphorylation of p38 in HT29 cells showed that in HT29 cells expressing IGPR-1, phosphorylation of p38 was significantly inhibited (Figure 2d), suggesting that the prosurvival effect of IGPR-1 in CRC tumor cells in the absence of adhesion to ECM is mediated by reducing activity of the stress-induced p38.