In the initial single variable model used to estimate correlations between each biochemical liver function test and histological diagnoses, we observed a significant reduction in serum albumin concentrations (P < 0.001) as well as significant reductions in AST (P = 0.002), and ALT (P = 0.02) values in patients with clinically important fatty livers after RYGB. This evidence concerns the gene ALB and fatty liver disease.