IL17A and autoimmune polyendocrine syndrome type 1: Another study assessed Th17 responses of PBMCs to Candida and non-Candida species stimuli finding that PBMCs from APS-1 patients had a normal or increased IL-17 production and Th17 cell proliferation, although only in the absence of their own plasma, which had an inhibitory effect on both IL-17 production and Th17 cell proliferation (34).