Next, to further assess whether the expression of the gene encoding for the ribosomal protein L6 undergoes transcriptional regulation when fungal cells interact in vivo with host cells, we took advantage of the recently standardized model of sporotrichosis in larvae from G. mellonella (Clavijo-Giraldo et al., 2016), and infected the insect with yeast-like cells from the strain 1099-18 (ATCC MYA-4821). This evidence concerns the gene RPL6 and sporotrichosis.