The inhibition of these key enzymes may have important biological consequences, such as: (i) inhibition of complement-mediated lysis, (ii) decrease in C3a and C5a (anaphylatoxins) generation (these small complement fragments are essential in the recruitment of blood cells to the infection site), and (iii) decreased opsonization, which mediates phagocytosis of pathogens during the infection (Cestari et al., 2012). Here, C5 is linked to infection.