On the other hand, avoidance of hypoglycaemia is not as simple as relaxing HbA1c targets – Munshi et al [46] demonstrated using continuous glucose monitoring that 65% of a group of (mainly insulin-treated) elderly patients with HbA1c >8% experienced at least one episode of hypoglycaemia (blood glucose <3.9 mmol/L) over 3 days’ monitoring. This evidence concerns the gene INS and Hypoglycemia.