We have previously described that mitotic clones mutant for Apc and Apc2 that co-express the oncogenic form of Ras, UAS-rasV12 under the control of esg-Gal4 driver line (from now on denoted as Apc-Ras clones), develop as tumor overgrowths in the Drosophila intestine. The gene discussed is APC; the disease is neoplasm.