CD4 and neoplasm: In addition, by using CD4 T cells from TCR transgenic mice recognizing tyrosinase-related protein 1 (TRP-1)35, a melanocyte differentiation antigen naturally expressed by B16F10 melanoma cells, we also found that the anticancer activity of TH9 cells was similarly enhanced by chloroquine in the non-OVA B16F10 tumour model (Fig. 6b).