Consistent with previously published data5, we identified substantial numbers of CD8+ T cells restricted to two prevailing mutant tumour epitopes, mLama4 (10.2 ± 3.2% as the mean ± SEM of five experiments) and mAlg8 (9.9 ± 3.8% as the mean ± SEM of five experiments), infiltrating the tumours of tumour-bearing mice. This evidence concerns the gene CD8A and neoplasm.