CSF3 and neutropenia: Considering the role of G-CSF, a sensitivity analysis was performed and found no apparent significant difference in the incidence of grade 3 or 4 neutropenia between the two arms (RR = 0.85, 95% CI = 0.05 to 13.65, P = 0.91; χ2 = 50.81, P < 0.00001, I2 = 96 %).