Circulating FBG (WMD: 27.471 mg/dL, 95% CI: 6.350 to 48.591), fasting insulin (WMD: 5.748 mU/L, 95% CI: 2.682 to 8.814), TG (WMD: 11.783 mg/dL, 95% CI: 0.113 to 23.453) and HOMA-IR (WMD: 2.360, 95% CI: 0.222 to 1.498) levels were significantly higher in CAD patients than in controls, while circulating HDLC (WMD: -4.020 mg/dL, 95% CI: -5.801 to -2.239) was significantly lower. This evidence concerns the gene INS and coronary artery disorder.