STAT3 and Familial prostate cancer: Morusin inhibited glioblastoma cell growth by regulating EGFR and DR5 to induce TRAIL sensitization both in vivo and in vitro [18, 19], suppressed breast cancer cell growth via C/EBPβ- and PPARγ-mediated lipoapoptosis [20], and induced cell death by inactivating STAT3 signaling in prostate cancer cells [21].