BRAF and diffuse midline glioma: The versatility of the MS technique makes it implementable with other new diagnostic markers; indeed, the MS tests could be also extended with the detection of other hotspot mutations, such as BRAF V600E, typical of few types of glioma, as epitheliod glioblastoma, or H3 K27M for diffuse midline gliomas, characteristic of pediatric patients [6].