In the overall patient population, mPFS and mOS were 6 (95%CI, 5-7) and 20 months (95%CI, 14-26), respectively (Figure 1), with no differences by molecular subtype, being mPFS 5.8 months (range, 4.9-6.8) in “Luminal B”, and 7 months (range, 4.7-9.2) in “HER2 enriched” tumours (p=0.29) (Supplementary Table 2). This evidence concerns the gene ERBB2 and neoplasm.