Furthermore, there were no significant differences observed between Wip1 expression and other clinicopathologic features, such as gender (P=0.79), age (P=0.86), Tumor differentiation (P=0.82), HBV infection (P=0.34), Tumor focality(P=0.75), Clinical T stage (P=0.32) or Vascular invasion (P=0.33). This evidence concerns the gene PPM1D and neoplasm.