Consistent with the results of alginate-encapsulated tumor cell assay, MVD assay and quantification results demonstrated that either DESI2 or IP10 significantly reduced the MVD of tumors from glucose- or pVITRO2-treated group, while DESI2 combined with IP10 further reduced the MVD (Figure 5C and 5D). This evidence concerns the gene CXCL10 and neoplasm.