Due to its possible positivity in other tumors, such as melanomas, adenoid cystic carcinomas, Merkel cell carcinomas, Kaposi sarcomas, liposarcomas or leiomyomas/leiomyosarcomas, additional markers such DOG-1 (discovered on GIST-1) are used in most of the pathology laboratories [4, 5]. This evidence concerns the gene ANO1 and leiomyosarcoma.