Furthermore, in DSS induced colitis mouse model, AgomiR-324 by intraperitoneal injection significantly rescued the regulatory effects of Dicer on expressions of Hmgxb3 and Wasf-2 as evidenced by RT-PCR (Figure 6C and 6D) and immunohistochemistry staining (Figure 6E and 6F). This evidence concerns the gene WASF2 and colitis.