IL5 and asthma: However, there was a significant decrease in IL-5 (b = -0.74, 95%CI:-1.39;-0.09, p = 0.03), an increase in asthma-related quality of life over time (b = 0.27, 95%CI:0.15;0.40, p<0.001) and a reduction in sickness behaviour (b = -0.10, 95%CI:-0.20;0.00, p = 0.04).