An apparently different mechanism of enhanced infection of FcγR-negative cells from humans (A549), hamsters (BHK-21), mice (NIH3T3), and mosquitoes (C6-36) was demonstrated in experiments with dengue 2 virus (strain PL046) and a mab specific for the prM protein [55], which forms a complex with E in immature forms of flaviviruses [8]. This evidence concerns the gene FCGR2A and infection.