SNAI2 and cancer: Cell morphological studies revealed that the large isoform of DNAJB6a is crucial in reversal of mesenchymal properties and maintaining an epithelial-like characteristic in cancer cells, which correlates with the downregulation of mesenchymal markers such as vimentin, CHD2, Twist1, and Slug (SNAI2) and upregulation of keratin 18, an epithelial marker.