Erdj3 (DNAJB11), a stress-inducible DNAJ homolog, is abundant in the endoplasmic reticulum (ER) and binds to its cellular binding partner, Kaposi sarcoma-associated herpesvirus (KSHV) K1 protein, critically facilitating its partner’s expression and anti-apoptotic function to promote cancer [155]. This evidence concerns the gene DNAJB11 and cancer.