Among these patients undergoing surgical management for urolithiasis, 69 (10.4%) were found to have prediabetes with impaired fasting glucose and 149 (22.4%) had type 2 diabetes mellitus with dietary control or oral antihyperglycemic agents or insulin therapy, whereas 259 (38.9%) had HTN with or without antihypertensive medication use. The gene discussed is INS; the disease is urolithiasis.