In a study, Milunsky and friends were investigated 13486 pregnant women and they reported that 4-fold increase in low birth weight risk, 3-fold increase in placental abruption risk, 8-fold increase in intrauterine fetal death risk and 2.3-fold increase in preeclampsia risk when AFP value was above 2 MoM(22). This evidence concerns the gene AFP and preeclampsia.