PL levels decreased in TBI, PSD (moderate-to-severe) and TBI + PSD compared to controls. MUFA-containing PC and PI species decreased in TBI and TBI + PTSD groups but not in PTSD subjects, ether PC levels were lower in PTSD and TBI + PTSD compared to controls. Within PC and PE classes, ratio of AA- to DHA-containing species decreased in mTBI. APOE ε4 + subjects exhibited higher PL levels. This evidence concerns the gene APOE and post-traumatic stress disorder.