Recently, accumulation of IL17-releasing T cells in the kidney has been associated with renal and vascular dysfunction in animal models of HTN (McMaster et al., 2015; Itani et al., 2016b; Norlander et al., 2016), while mice deficient in IL17 are protected against Ang II HTN (Madhur et al., 2010). The gene discussed is IL17A; the disease is hypertensive disorder.