IL17A and cerebral infarction: In addition, the T cells, IL-23, and IL-17 that infiltrate into the ischemic cerebral tissues is critical to cerebral infarction formation and neurologic impairment, and IL-17 is reported to play an important role in the delayed phase of ischemia and reperfusion, namely, at the time of neuronal cell apoptosis and necrosis (Shichita et al., 2009).