Moreover, Positive staining of Podoplanin was also significantly correlated with onset age (P < 0.0001), lymph node metastasis (P = 0.028), vascular space involvement (P < 0.0001), lymphatic invasion (P < 0.0001), deep stromal invasion (P = 0.007), positive parametrium (P = 0.029), disease recurrence (P = 0.006), and the clinical prognosis of patients (P = 0.004) (Table 2). This evidence concerns the gene PDPN and metastatic malignant neoplasm in the lymph nodes.