Similarly total HLM counts made from whole tissue analysis of TRAMP-C2 (Fig. 4e) and Myc-CaP (Fig. 4f) did not exhibit changes in all organs (p > 0.05), but Myc-CaP prostate tumor HLMs exhibited an increase with L1 (p < 0.001). This evidence concerns the gene C2 and prostate neoplasm.