The CD68+ macrophage quantity vs. size distribution was quantified using exponential modeling (Fig. 2c), and showed the sizes of the CD68+ macrophages were similar in both model’s tissues (Fig. 2d), and were more numerous in TRAMP-C2 prostate tumors (p < 0.01), while their frequency in livers and spleens was equivalent (p > 0.05) between the two models (Fig. 2e). This evidence concerns the gene CD68 and prostate neoplasm.