There was no significant difference in the mRNA expression of TAGLN2 both in CD19+ B-cells (n = 9) and CD19+CD27+ memory B-cells (n = 14) isolated from the peripheral blood of SLE patients compared to those from healthy donors (n = 6 and 11, respectively) (p>0.05) (Fig 2E). Here, TAGLN2 is linked to systemic lupus erythematosus.