Hemoglobin (11.7 vs. 14.2g/dl, p<0.001) and albumin (43.4 vs. 46.7g/l, p<0.001) were lower but phosphate (1.6 vs. 1.2mmol/l, p<0.001), iPTH (36.7 vs. 3.6pmol/l, p<0.001), hs-CRP (7.3 vs. 2.4mg/l, p<0.001), NT-pro-BNP (576.9 vs. 8.3pmol/L, p<0.001) and Troponin-T (36.1 vs. 5.1μg/L, P<0.001) were higher in the CKD patients compared to the HTN group. This evidence concerns the gene NPPB and chronic kidney disease.