SOD1 and amyotrophic lateral sclerosis: Recent results have shown that aspirin reduces SOD-1 aggregation in amyotrophic lateral sclerosis (ALS) and decreases amyloid aggregates in Alzheimer’s diseases (AD) by donating its acetyl to decrease phosphorylation, which suggests that acetylation might contribute to the neuroprotective and lifespan extension effects of aspirin [13].