AFP and neoplasm: However, in the multivariate regression analysis, only TACE and sorafenib combination (HR, 0.35; 95% CI, 0.15–0.81), Child–Pugh score (HR, 1.84; 95% CI, 1.09–3.09), maximum tumor size (HR, 1.29; 95% CI, 1.10–1.52), and serum AFP >200 ng/mL (HR, 2.55; 95% CI, 1.08–6.00) were independent prognostic factors for patient survival.