QNZ treatment decreased caspase-12 cleavage as indicatedby increasing full-length caspase-12, and abrogated caspase-3 cleavage following BFA incervical tumor cells, without blocking the inhibition of caspase-12 and caspase-3 mRNAfollowing BFA treatment (Supplementary Figure 3). Here, CASP12 is linked to neoplasm.