This could explain some of the divergences in the differentiation patterns of this tumor, considering for example the potential for multidirectional proliferation of the Wilm’s tumor (which can express vimentin, NSE and cytokeratin), the myogenic differentiation often observed in its stromal component, and the inclination of Ewing’s tumor to show a neurogenic differentiation. This evidence concerns the gene ENO2 and Nephroblastoma.