Laboratory data showed; anaemia Hb 12,2g/dl, leukopenia 8510/μL, platelet was markedly decreased to 18,000/μL, hepatic cytolysis; ALAT 159U/L; ASAT 140U/L; total bilirubin 151mg/l; Direct bilirubin 109mg/l; and biological cholestasis; alkaline phosphatase (ALP) of 174; Gamma glutamyltransferase of 252UI/L activated partial thromboplastin time (PTT) was normal;Prothrombin Time (PT) of 50%. The gene discussed is GSTM1; the disease is Decreased total leukocyte count.