GSTM1 and Decreased total leukocyte count: The newbornhas subsequently presented a reappearance of jaundice and petechiae, laboratory data showed: Hb 10g/dl, leukopenia 2750/μL, platelet at 73000/μL, ALAT 91U/L; ASAT 123U/L; total bilirubin 101mg/l; Direct bilirubin 77mg/l, with a rescinding of the viral load (54305UI/ml)making suspected a resistanceto ganciclovir or a reactivation of CMV in relation with breastfeedingtherefore we had switched to an oral antiviral drug (valganciclovir 30 mg/kg/day) for fourth week.