CASP3 and cancer: Overexpression of CUDR induces resistance to doxorubicin and etoposide, decreases drug-induced apoptosis, as well as expression and activity of caspase-3, promotes anchorage-independent growth in squamous carcinoma cells, demonstrating that CUDR may regulate cancer-drug sensitivity through caspase 3-dependent apoptosis [68] (See, Table 1).