Compared with the N group, the relative expressions of NLRP3, ASC, Caspase-1, and IL-1β significantly increased in the AD (p < 0.01), MA (p < 0.01), and M groups (p < 0.01 or 0.05), with the exception of ASC and Caspase-1, which did not show significant differences in the MA group (p > 0.05). The gene discussed is CASP1; the disease is Alzheimer disease.