Past experience (the analytical domain of Siegrist and colleagues’ conceptual model [23]) may play a role here too, as older participants ‘experienced’ stories of cancer as “the Big C” during an earlier time when advancements in treatments and overall survival were poorer, and so existing tests could truly be seen as “better than nothing.” Moreover, they would have had more cumulative exposure to “early detection” messages, as well as more experience having mammograms and PSA tests, thus being more comfortable with them as routine services even if they held the potential for false positives. Here, KLK3 is linked to cancer.